Warning: mysql_connect(): Headers and client library minor version mismatch. Headers:100029 Library:50552 in /data/NANOTECH/wap/inc/SQLclient.inc.php on line 64 NanodatenSprache wechseln: English

Suchbegriff oder Artikelnummer
 
Artikelbezeichnung und Beschreibung durchsuchen
Auch Unternehmensverzeichnis durchsuchen


hERG Safety Screening
Cytocentrics AG offers highly qualitative and reliable in-vitro screening for interactions between drug candidates and hERG ion channels. Cytocentrics AG uses the whole cell patch clamp technique to generate concentration-response data of drug candidates blocking the hERG ion channels. Cytocentrics performs all data with conventional and automated patch clamp (Dynaflow™, CytoPatch™ ).

Assay specifications include:
- High qualitative whole cell patch clamp recordings
- from HEK293 cells expressing the hERG ion channel.
- Determination of IC50 from hERG tail currents.
- Repetitive measurements for each compound concentration.
- Positive and negative control experiments using reference compounds.
- hERG trafficking interference.
- Screening in GLP and non-GLP environment.
- Assay adaptation to client requirements.
- Full scientific review and QA report.

Company
Cytocentrics AG
Joachim-Jungius-Str. 9
18059 Rostock (Deutschland)
Homepage: http://www.cytocentrics.com/de/

Contact
Dr. Christa Nutzhorn
Phone: +49 (0) 381 4059-640
Fax: +49 (0) 381 4059-647
info@cytocentrics.com